| Target | |
|---|---|
| Synonyms | NTN;NTT;CXC3;CXC3C;SCYD1;ABCD-3;C3Xkine;fractalkine;neurotactin |
| Description | Recombinant human CX3CL1 Protein with C-terminal 6×His tag |
| Delivery | In Stock |
| Uniprot ID | P78423 |
| Expression Host | HEK293 |
| Tag | C-6×His Tag |
| Molecular Characterization | CX3CL1(Gln25-Gln341) 6×His tag |
| Molecular Weight | The protein has a predicted molecular mass of 34.4 kDa after removal of the signal peptide. |
| Purity | The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining. |
| Formulation & Reconstitution | Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution. |
| Storage & Shipping | Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature. |
| Background | This gene belongs to the CX3C subgroup of chemokines, characterized by the number of amino acids located between the conserved cysteine residues. This is the only member of the CX3C subgroup, which contains three amino acids between cysteine residues, resulting in a Cys-X-X-X-Cys configuration. The encoded protein contains an extended mucin-like stalk with a chemokine domain on top, and exists in both a membrane-anchored form where it acts as a binding molecule, or, in soluble form, as a chemotactic cytokine. The mature form of this protein can be cleaved at the cell surface, yielding different soluble forms that can interact with the G-protein coupled receptor, C-X3-C motif chemokine receptor 1 gene product. This gene plays a role in a wide range of diseases, including cancer, vasculitis, neuropathies, atherosclerosis, inflammatory diseases, and in human immunodeficiency virus infections. [provided by RefSeq, Sep 2017] |
| Usage | Research use only |
| Conjugate | Unconjugated |
Human CX3CL1 Protein, His Tag
Price: 10μg $75.00; 50μg $259.00 ; 100μg $389.00
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Figure 1. Human CX3CL1 Protein, His Tag on SDS-PAGE under reducing condition.
Figure 2. ELISA plate pre-coated by 2 μg/mL (100 μL/well) Human CX3CL1 Protein, His Tag (PME101343) can bind Anti-CX3CL1(quetmolimab biosimilar) mAb (BME100259) in a linear range of 0.64–80 ng/mL.
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Biosimilar reference antibodies
SKU: BME100259 Target: CX3CL1
Application: ELISA
Price: 50 μg $82.00 ; 100 μg $162.00