Target | |
---|---|
Synonyms | AIEFL; IMD57; RIP; RIP-1; RIP1 |
Description | Purified recombinant protein of Human receptor (TNFRSF)-interacting serine-threonine kinase 1 (RIPK1), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
Delivery | 1 week |
Uniprot ID | Q13546 |
Expression Host | E. coli |
Tag | N-His |
Molecular Characterization | N/A |
Molecular Weight | 75.8 kDa |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Formulation & Reconstitution | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl |
Storage & Shipping | Store at -80°C. |
Background | This gene encodes a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. [provided by RefSeq, Aug 2017] |
Usage | Research use only |
Conjugate | Unconjugated |
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Human RIP (RIPK1) (NM_003804) Protein
Price:50 μg¥2,040.00 ;
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