Human SINHCAF (NM_001135812) Protein

Price:50 μg￥2,040.00 ;

SKU: PME47364 Category: ECD Proteins

Target	SINHCAF
Synonyms	C12orf14; FAM60A; L4; TERA
Description	Purified recombinant protein of Human family with sequence similarity 60, member A (FAM60A), transcript variant 3, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Delivery	2-3 weeks
Uniprot ID	Q9NP50
Expression Host	E. coli
Tag	N-His
Molecular Characterization	N/A
Molecular Weight	24.7 kDa
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Formulation & Reconstitution	25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl.
Storage & Shipping	Store at -80°C.
Background	Subunit of the Sin3 deacetylase complex (Sin3/HDAC), this subunit is important for the repression of genes encoding components of the TGF-beta signaling pathway (PubMed:22865885, PubMed:22984288). Core component of a SIN3A complex (composed of at least SINHCAF, SIN3A, HDAC1, SAP30, RBBP4, OGT and TET1) present in embryonic stem (ES) cells. Promotes the stability of SIN3A and its presence on chromatin and is essential for maintaining the potential of ES cells to proliferate rapidly, while ensuring a short G1-phase of the cell cycle, thereby preventing premature lineage priming (By similarity).[UniProtKB/Swiss-Prot Function]
Usage	Research use only
Conjugate	Unconjugated