Human ABCB7 (NM_004299) Protein

Price:50 μg￥1,948.00 ;

SKU: PME48961 Category: ECD Proteins

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Target	ABCB7
Synonyms	ABC7; ASAT; Atm1p; EST140535
Description	Purified recombinant protein of Human ATP-binding cassette, sub-family B (MDR/TAP), member 7 (ABCB7), nuclear gene encoding mitochondrial protein,Val431-End, with N-terminal His tag, expressed in E. coli, 50ug
Delivery	1 week
Uniprot ID	O75027
Expression Host	E. coli
Tag	N-His
Molecular Characterization	N/A
Molecular Weight	35.8 kDa
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Formulation & Reconstitution	50mM Tris, 8M Urea, pH8.0.
Storage & Shipping	Store at -80°C.
Background	The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis. Mutations in this gene have been associated with mitochondrial iron accumulation and isodicentric (X)(q13) and sideroblastic anemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2012]
Usage	Research use only
Conjugate	Unconjugated

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