Human Caspase 4 (CASP4) (NM_001225) Protein

Price:50 μg￥2,040.00 ;

SKU: PME47232 Category: ECD Proteins

Target	Caspase 4
Synonyms	ICE(rel)II; ICEREL-II; ICH-2; Mih1; Mih1/TX; TX
Description	Purified recombinant protein of Human caspase 4, apoptosis-related cysteine peptidase (CASP4), transcript variant alpha, with N-terminal HIS tag, expressed in E.Coli, 50ug
Delivery	1 week
Uniprot ID	P49662
Expression Host	E. coli
Tag	N-His
Molecular Characterization	N/A
Molecular Weight	43.1 kDa
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Formulation & Reconstitution	25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Storage & Shipping	Store at -80°C.
Background	This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated