Human CD63 full length protein-synthetic nanodisc

Name: Human CD63 full length protein-synthetic nanodisc
SKU: FLP100030
Availability: InStock

Price: 10 μg $900.00 ; 50 μg $4400.00 ; 100 μg $8000.00

SKU: FLP100030 Category: Full Length Transmembrane Proteins Tag: synthetic nanodisc

Datasheet

MSDS

Product Data Dima FAQ

Tag	C-Flag Tag
Target	CD63
Synonyms	LAMP-3; ME491; MLA1; OMA81H; TSPAN30
Description	Human CD63 full length protein-synthetic nanodisc
Delivery	In Stock
Uniprot ID	P08962
Expression Host	HEK293
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Lysosome
Molecular Weight	The human full length CD63 protein has a MW of 25.6 kDa
Formulation & Reconstitution	Lyophilized from nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0). Normally 5% – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	The protein is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
Usage	Research use only
Conjugate	Unconjugated

Images Dima FAQ

FLP100030-CD63-Fig.1-Elisa-1.jpg
Figure 1. Elisa plates were pre-coated with Flag Tag CD63-Nanodisc (0.2μg/per well). Serial diluted anti-CD63 monoclonal antibody (DMC100425) solutions were added, washed, and incubated with secondary antibody before Elisa reading. From above data, the EC50 for anti-CD63 monoclonal antibody binding with CD63-Nanodisc is 94.22ng/ml.
FLP100030-CD63-Fig.2-SDS-PAGE-1.jpg
Figure 2. Human CD63-Nanodisc, Flag Tag on SDS-PAGE

Figure 3. ELISA assay evaluating the stability of Human CD63 full-length protein in synthetic nanodiscs (SKU# FLP100030).

Figure 4. ELISA assay evaluating the stability of Human CD63 full-length protein in synthetic nanodiscs (SKU# FLP100030).

Human CD63 full length protein-synthetic nanodisc

Product Data Dima FAQ

Images Dima FAQ

相关产品

Login