Target | |
---|---|
Synonyms | Cdh7; CDH7L3 |
Description | Purified recombinant protein of Human cadherin 20, type 2 (CDH20), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
Delivery | 2-3 weeks |
Uniprot ID | Q9HBT6 |
Expression Host | E. coli |
Tag | N-His |
Molecular Characterization | N/A |
Molecular Weight | 85.1 kDa |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Formulation & Reconstitution | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Storage & Shipping | Store at -80°C. |
Background | This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008] |
Usage | Research use only |
Conjugate | Unconjugated |
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Human CDH20 (NM_031891) Protein
Price:50 μg¥2,040.00 ;
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