Human Fbx32 (FBXO32) (NM_148177) Protein

Price:50 μg￥2,040.00 ;

SKU: PME47471 Category: ECD Proteins

Target	Fbx32
Synonyms	Fbx32; MAFbx
Description	Purified recombinant protein of Human F-box protein 32 (FBXO32), transcript variant 2, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Delivery	2-3 weeks
Uniprot ID	Q0VAQ6
Expression Host	E. coli
Tag	N-His
Molecular Characterization	N/A
Molecular Weight	24.5 kDa
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Formulation & Reconstitution	50mM Tris,8M Urea,pH8.0.
Storage & Shipping	Store at -80°C.
Background	This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Usage	Research use only
Conjugate	Unconjugated