Human HIP2 (UBE2K) (NM_005339) Protein

Price:20 μg￥2,900.00 ; 100 μg￥9,998.00 ; 1 mg￥36,000.00

SKU: PME34382 Category: ECD Proteins

Target	HIP2
Synonyms	E2-25K; HIP2; HYPG; LIG; UBC1
Description	Recombinant protein of human ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) (UBE2K), transcript variant 1
Delivery	2-3 weeks
Uniprot ID	P61086
Expression Host	HEK293T
Tag	C-Myc/DDK
Molecular Characterization	N/A
Molecular Weight	22.2 kDa
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Formulation & Reconstitution	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Storage & Shipping	Store at -80°C.
Background	The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Usage	Research use only
Conjugate	Unconjugated