Target | |
---|---|
Synonyms | L21mt; MRP-L21 |
Description | Purified recombinant protein of Human mitochondrial ribosomal protein L21 (MRPL21), nuclear gene encoding mitochondrial protein, transcript variant 4, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
Delivery | 2-3 weeks |
Uniprot ID | Q7Z2W9 |
Expression Host | E. coli |
Tag | N-His |
Molecular Characterization | N/A |
Molecular Weight | 22.6 kDa |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Formulation & Reconstitution | 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. |
Storage & Shipping | Store at -80°C. |
Background | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD). [provided by RefSeq, Jul 2008] |
Usage | Research use only |
Conjugate | Unconjugated |
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Human MRPL21 (NM_181514) Protein
Price:50 μg¥2,040.00 ;
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