Human Nectin-4(238-349) Protein, hFc Tag

Name: Human Nectin-4(238-349) Protein, hFc Tag
SKU: PME101606
Availability: InStock

Price: 10μg $90.00 ; 50μg $320.00 ; 100μg $480.00

SKU: PME101606 Category: ECD Proteins

Datasheet

MSDS

Product Data Negative control Dima FAQ

Target	Nectin-4
Synonyms	LNIR; PRR4; EDSS1; PVRL4; NECTIN4
Description	Recombinant human Nectin-4(238-349) Protein with C-terminal human Fc tag
Delivery	In Stock
Uniprot ID	Q96NY8
Expression Host	HEK293
Tag	C-Human Fc tag
Molecular Characterization	Nectin-4(His238-Ser349) hFc(Glu99-Ala330)
Molecular Weight	The protein has a predicted molecular mass of 38.3 kDa after removal of the signal peptide. The apparent molecular mass of Nectin-4(238-349)-hFc is approximately 35-55 kDa due to glycosylation.
Purity	The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
Formulation & Reconstitution	Lyophilized from sterile PBS, pH 7.4. Normally 5 % – 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions of reconstitution.
Storage & Shipping	Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
Background	This gene encodes a member of the nectin family. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.[provided by RefSeq, Jan 2011]
Usage	Research use only
Conjugate	Unconjugated