Target | |
---|---|
Synonyms | MST077; MSTP077 |
Description | Purified recombinant protein of Human NOP2/Sun domain family, member 3 (NSUN3), full length, with N-terminal HIS tag, expressed in E.Coli, 50ug |
Delivery | 2-3 weeks |
Uniprot ID | Q9H649 |
Expression Host | E. coli |
Tag | N-His |
Molecular Characterization | N/A |
Molecular Weight | 38.1 kDa |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Formulation & Reconstitution | 50mM Tris, 8M Urea, pH8.0. |
Storage & Shipping | Store at -80°C. |
Background | Mitochondrial tRNA methyltransferase that mediates methylation of cytosine to 5-methylcytosine (m5C) at position 34 of mt-tRNA(Met) (PubMed:27497299, PubMed:27214402, PubMed:27356879). mt-tRNA(Met) methylation at cytosine(34) takes place at the wobble position of the anticodon and initiates the formation of 5-formylcytosine (f(5)c) at this position (PubMed:27497299, PubMed:27214402, PubMed:27356879). mt-tRNA(Met) containing the f(5)c modification at the wobble position enables recognition of the AUA codon in addition to the AUG codon, expanding codon recognition in mitochondrial translation (PubMed:27497299, PubMed:27356879).[UniProtKB/Swiss-Prot Function] |
Usage | Research use only |
Conjugate | Unconjugated |
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Human NSUN3 (NM_022072) Protein
Price:50 μg¥2,040.00 ;
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