Human PRAK (MAPKAPK5) (NM_003668) Protein

Price:50 μg￥2,040.00 ;

SKU: PME47247 Category: ECD Proteins

Target	PRAK
Synonyms	MAPKAP-K5; MK-5; MK5; PRAK
Description	Purified recombinant protein of Human mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), transcript variant 1, full length, with N-terminal HIS tag, expressed in E.Coli, 50ug
Delivery	2-3 weeks
Uniprot ID	Q8IW41
Expression Host	E. coli
Tag	N-His
Molecular Characterization	N/A
Molecular Weight	53.9 kDa
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Formulation & Reconstitution	25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl
Storage & Shipping	Store at -80°C.
Background	The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
Usage	Research use only
Conjugate	Unconjugated