Human Proteasome subunit beta type 2 (PSMB2) (NM_002794) Protein

Price:20 μg￥2,900.00 ; 100 μg￥9,998.00 ; 1 mg￥36,000.00

SKU: PME35118 Category: ECD Proteins

Target	Proteasome subunit beta type 2
Synonyms	HC7-I
Description	Recombinant protein of human proteasome (prosome, macropain) subunit, beta type, 2 (PSMB2)
Delivery	2-3 weeks
Uniprot ID	P49721
Expression Host	HEK293T
Tag	C-Myc/DDK
Molecular Characterization	N/A
Molecular Weight	22.7 kDa
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Formulation & Reconstitution	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Storage & Shipping	Store at -80°C.
Background	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Usage	Research use only
Conjugate	Unconjugated