Target | |
---|---|
Synonyms | R51H2; RAD51L1; REC2 |
Description | Purified recombinant protein of Human RAD51-like 1 (S. cerevisiae) (RAD51L1), transcript variant 3, with N-terminal HIS tag, expressed in E.Coli, 50ug |
Delivery | 2-3 weeks |
Uniprot ID | O15315 |
Expression Host | E. coli |
Tag | N-His |
Molecular Characterization | N/A |
Molecular Weight | 42 kDa |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Formulation & Reconstitution | 50mM Tris,8M Urea,pH8.0. |
Storage & Shipping | Store at -80°C. |
Background | The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016] |
Usage | Research use only |
Conjugate | Unconjugated |
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Human Rad51L1 (RAD51B) (NM_133509) Protein
Price:50 μg¥2,040.00 ;
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