Human WDR91 (NM_014149) Protein

Price:20 μg￥2,900.00 ; 100 μg￥9,998.00 ; 1 mg￥36,000.00

SKU: PME33161 Category: ECD Proteins

Target	WDR91
Synonyms	HSPC049; SORF-1; SORF1
Description	Recombinant protein of human WD repeat domain 91 (WDR91)
Delivery	2-3 weeks
Uniprot ID	A4D1P6
Expression Host	HEK293T
Tag	C-Myc/DDK
Molecular Characterization	N/A
Molecular Weight	83.2 kDa
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Formulation & Reconstitution	25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Storage & Shipping	Store at -80°C.
Background	Functions as a negative regulator of the PI3 kinase/PI3K activity associated with endosomal membranes via BECN1, a core subunit of the PI3K complex. By modifying the phosphatidylinositol 3-phosphate/PtdInsP3 content of endosomal membranes may regulate endosome fusion, recycling, sorting and early to late endosome transport (PubMed:26783301). It is for instance, required for the delivery of cargos like BST2/tetherin from early to late endosome and thereby participates indirectly to their degradation by the lysosome (PubMed:27126989). May play a role in meiosis (By similarity).[UniProtKB/Swiss-Prot Function]
Usage	Research use only
Conjugate	Unconjugated